How to build running endurance from scratch? ?

You can run, you are just frustrated because you are out of breath after a quarter mile. The best marathoners didn't start off running 25 miles, they built up to it. If all you can run is a quarter mile, fine start there. Run a a quarter mile , get your breath back, then run another. Do that for a half hour. As you get in better shape, reduce the rest until you eliminate it.